team >

current members

angela oliveira pisco

nationality

Portuguese

role

Postdoc

qualifications

• PhD in Systems Biology, The University of Manchester, UK (2013)
• MSc in Biomedical Engineering, Instituto Superior Tecnico, Lisbon, Portugal (2004)

research project title

'Systems Analysis of Transient Perturbations Along Developmental Trajectories'

core expertise

• Bioinformatics
• Cell culture
• Flow cytometry
• Genomics
• Mathematical modelling
• Single-cell technologies
• Transcriptomics

publications

[Full PubMed list]

•  ‘A genome-wide screen identifies YAP/WBP2 interplay conferring growth advantage on human epidermal stem cells.’ Walko G, Woodhouse S, Pisco AO, Rognoni E, Liakath-Ali K, Lichtenberger BM, Mishra A, Telerman SB, Viswanathan P, Logtenberg M, Renz LM, Donati G, Quist SR, Watt FM. Nat Commun. 2017 Mar 23;8:14744. doi: 10.1038/ncomms14744. PMID: 28332498 [PubMed]

•  'Inhibition of β-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing.' Rognoni E, Gomez C, Pisco AO, Rawlins EL, Simons BD, Watt FM, Driskell RR. Development. 2016 Jun 10. pii: dev.131797. PMID: 27287810 [PubMed]

•  'Reduced intracellular drug accumulation in drug-resistant leukemia cells is not solely due to MDR-mediated efflux but also to decreased uptake.' Pisco, A.O., Jackson, D., Huang, S., Frontiers in Oncology 4:306, October 2014, DOI: 10.3389/fonc.2014.00306 PMID: 25401091 [PubMed]

•  'Nonequilibrium Population Dynamics Of Phenotype Conversion of Cancer Cells.' Zhou, J., Pisco, A.O., Qian, H., Huang, S., PLoS One 9(12):e110714, 01 December 2014, DOI: 10.1371/journal.pone.0110714 PMID: 25438251 [PubMed]

•  'Non-Darwinian dynamics of therapy-induced persistent cancer drug resistance.' Pisco, A.O., Brock, A., Zhou, J., Moor, A., Mojtahedi, M., Jackson, D., Huang, S., Nature Communications 4, Article number: 2467, doi:10.1038/ncomms3467, 18 September 2013 PMID: 24045430 [PubMed]

•  'MicroRNA-9 Reveals Regional Diversity of Neural Progenitors along the Anterior-Posterior Axis.' Bonev, B., Pisco, A.,Papalopulu, N, Developmental Cell, Volume 20, Issue 1, Pages 19-32, 18 January 2011 PMID: 21238922 [PubMed]

•  'Partitioning of human antibodies in polyethylene glycol-sodium citrate aqueous two-phase systems.' Azevedo, A.M., Gomes, A.G., Rosa, P.A.J., Ferreira, I.F., Pisco, A.M.M.O., Aires-Barros, M.R., Separation and Purification Technology, Volume 65, Issue 1, Pages 14-21, 2 February 2009

•  'Affinity-enhanced purification of human antibodies by aqueous two-phase extraction.' Azevedo, A.M., Gomes, A.G., Rosa, P.A.J., Ferreira, I.F., Pisco, A.M.M.O., de Vries, J., Korporaal, R., Visser, T. J., Aires-Barros, M.R., Separation and Purification Technology, Volume 65, Issue 1, Pages 31-39, 2 February 2009