stem cells in their environment

team >

christina philippeos

nationality

Greek / South African

role

Postdoc

qualifications

  • PhD in Cell Biology, King's College London (2014)
  • MSc. in Biochemistry, University of Johannesburg, South Africa (2007)
  • BSc. in Natural and Environmental Sciences, Rand Afrikaans University, South Africa (2004)

research project title

'Utilising human skin fibroblasts for therapeutic applications in wound repair and resolving scar formation.'

core expertise

  • Cell Biology
  • Wound healing
  • IHC and Confocal microscopy
  • Flow Cytometry

publications

[Full PubMed list]

  • ‘Differential Expression of Insulin-Like Growth Factor 1 and Wnt Family Member 4 Correlates With Functional Heterogeneity of Human Dermal Fibroblasts‘. Culley, O.J., Louis, B., Philippeos, C., Oulès B., Tihy, M., Segal, J.M., Hyliands, D., Jenkins, G., Bhogal, R. K., Siow, R. C., Watt, F.M. Front Cell Dev Biol. 2021;9:717.
  • ‘Contribution of GATA6 to homeostasis of the human upper pilosebaceous unit and acne pathogenesis’. Oulès B, Philippeos C, Segal J, Tihy M, Vietri Rudan M, Cujba AM, Grange PA, Quist S, Natsuga K, Deschamps L, Dupin N, Donati G, Watt FM. Nat Commun. 2020 Oct 20;11(1):5067. PMID: 33082341 [PubMed]
  • ‘Regulatory T Cell Extracellular Vesicles Modify T-Effector Cell Cytokine Production and Protect Against Human Skin Allograft Damage’. Tung SL, Fanelli G, Matthews RI, Bazoer J, Letizia M, Vizcay-Barrena G, Faruqu FN, Philippeos C, Hannen R, Al-Jamal KT, Lombardi G, Smyth LA. Front Cell Dev Biol. 2020;8:317. PMID: 32509778 [PubMed]
  • ‘Fibroblast state switching orchestrates dermal maturation and wound healing’. Rognoni E, Pisco AO, Hiratsuka T, Sipilä KH, Belmonte JM, Mobasseri SA, Philippeos C, Dilão R, Watt FM. Mol Syst Biol. 2018 Aug 29;14(8):e8174. PMID: 30158243 [PubMed]
  • ‘Loxl2 is dispensable for dermal development, homeostasis and tumour stroma formation’. Kober KI, Cano A, Géraud C, Sipilä K, Mobasseri SA, Philippeos C, Pisco AO, Stannard A, Martin A, Salvador F, Santos V, Boutros M, Rognoni E, Watt FM. PLoS One. 2018;13(6):e0199679. PMID: 29953488 [PubMed]
  • 'Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations.' Philippeos C, Telerman SB, Oulès B, Pisco AO, Shaw TJ, Elgueta R, Lombardi G, Driskell RR, Soldin M, Lynch MD, Watt FM. J Invest Dermatol. 2018 Apr;13 8(4):811-825. doi: 10.1016/j.jid.2018.01.016. Epub 2018 Jan 31. PMID: 29391249 [PubMed]
  • ‘Expression of a Chimeric Antigen Receptor Specific for Donor HLA Class I Enhances the Potency of Human Regulatory T Cells in Preventing Human Skin Transplant Rejection’. Boardman DA, Philippeos C, Fruhwirth GO, Ibrahim MA, Hannen RF, Cooper D, Marelli-Berg FM, Watt FM, Lechler RI, Maher J, Smyth LA, Lombardi G. Am J Transplant. 2017 Apr;17(4):931-943. PMID: 28027623. [PubMed]
  • 'Alginate Microencapsulated Hepatocytes Optimised for Transplantation in Acute Liver Failure' Jitraruch S, Dhawan A, Hughes RD, Filippi C, Soong D, Philippeos C, Lehec SC, Heaton ND, Longhi MS, Mitry RR. PLoS One. 2014; 9(12): e113609. PMID: 25438038 [PubMed]
  • 'Use of indocyanine green for functional assessment of human hepatocytes for transplantation'. Ho CM, Dhawan A, Hughes RD, Lehec SC, Puppi J, Philippeos C, Lee PH, Mitry RR. Asian J Surg. 2012; 35(1):9-15. PMID: 22726558 [PubMed]
  • 'Introduction to cell culture'. Philippeos C, Hughes RD, Dhawan A, Mitry RR. Methods Mol Biol. 2012; 806:1-13. PMID: 22057441 [PubMed]
  • 'Comparative 1H NMR-based metabonomic analysis of HIV-1 sera.' Philippeos C, Steffens FE, Meyer D. J Biomol NMR. 2009; 44:127–137. PMID: 19513588 [PubMed]